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Compendium of physical activities history11/25/2023 This is partly due to the enhanced cardiorespiratory adaptations it causes 14 and the protection it offers against the development of certain cancers 15, 16. For a given volume of physical activity, higher contributions of VPA are associated with additional mortality risk reduction 10, 11, 12, 13. The health effects of each time unit of physical activity are intensity dependent 10, 11, 12, 13. Besides, little evidence supports the previous guideline because questionnaires can typically capture only longer bouts (for example, ≥10 min) of physical activity and often concentrate on leisure time activities such as gym-based exercise, running and sports 8, 9. This recommendation contrasts with previous guidelines 6, 7 that did not recognize the health value of physical activity bouts lasting <10 min. New emphasis is placed on ‘all activity counts’ occurring across all life domains and regardless of bout duration. Recently updated guidelines 4, 5, based mostly on questionnaire-derived evidence, recommend 150–300 min of moderate-intensity activity or 75–150 min of vigorous-intensity physical activity (≥6 metabolic equivalents) per week. Physical activity is associated with reduced mortality risk 1, and reduced risk of CVD 1 and certain cancers 2, 3, 4. VILPA in nonexercisers appears to elicit similar effects to VPA in exercisers, suggesting that VILPA may be a suitable physical activity target, especially in people not able or willing to exercise. These results indicate that small amounts of vigorous nonexercise physical activity are associated with substantially lower mortality. We obtained similar results when repeating the above analyses for vigorous physical activity (VPA) in 62,344 UK Biobank participants who exercised (1,552 deaths, 35,290 women/27,054 men). Moreover, the sample median VILPA duration of 4.4 min per day was associated with a 26%–30% reduction in all-cause and cancer mortality risk and a 32%–34% reduction in CVD mortality risk. Compared with participants who engaged in no VILPA, participants who engaged in VILPA at the sample median VILPA frequency of 3 length-standardized bouts per day (lasting 1 or 2 min each) showed a 38%–40% reduction in all-cause and cancer mortality risk and a 48%–49% reduction in CVD mortality risk. Over an average follow-up of 6.9 years, during which 852 deaths occurred, VILPA was inversely associated with all three of these outcomes in a near-linear fashion. Here, we examined the association of VILPA with all-cause, cardiovascular disease (CVD) and cancer mortality in 25,241 nonexercisers (mean age 61.8 years, 14,178 women/11,063 men) in the UK Biobank. Wearable devices can capture unexplored movement patterns such as brief bursts of vigorous intermittent lifestyle physical activity (VILPA) that is embedded into everyday life, rather than being done as leisure time exercise.
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